Hubert H. Humphrey, Jr. died on January 13, 1978 of bladder cancer at his home in Waverly, Minnesota. His body lay in state in the rotunda of both the United States Capitol and the Minnesota State Capitol, and was interred in Lakewood Cemetery in Minneapolis. Old friends and opponents of Humphrey, from Gerald Ford and Richard Nixon to President Carter and Vice-President Walter Mondale paid their final respects. "He taught us how to live, and finally he taught us how to die", said Mondale.
Humphrey spent his last days calling old political acquaintances. One call was to Richard Nixon inviting him to his upcoming funeral which he accepted. Living in the hospital, Humphrey went from room to room, cheering up other patients by telling jokes and listening to them.
At the time of his death, he was survived by his children: Hubert Humphrey III, Nancy Faye Humphrey (1939–2003), Robert Humphrey and Douglas Humphrey.
His wife, Muriel Humphrey, was appointed by Minnesota's governor Rudy Perpich to serve in the US Senate until a special election to fill the term was held. She did not seek election to finish her husband's term in office.
Muriel Humphrey remarried in 1981 (to Max Brown) and took the name Muriel Humphrey Brown. She died in 1998 at the age of 86 and is interred next to Hubert Humphrey.